Artigos Científicos

Seleção de referências e estudos que embasam nossas fórmulas e filosofia.

Oral Supplementation of Collagen Peptides Improves Skin Hydration by Increasing the Natural Moisturizing Factor Content in the Stratum Corneum: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

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Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology

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Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression

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Signal Peptides – Promising Ingredients in Cosmetics

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Collagen study advances for photoaging skin

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The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials

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The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials

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Low-molecular-weight collagen peptides supplement promotes a healthy skin: A randomized, double-blinded, placebo-controlled study

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Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study

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Oral Supplementation of Low-Molecular-Weight Collagen Peptides Reduces Skin Wrinkles and Improves Biophysical Properties of Skin: A Randomized, Double-Blinded, Placebo-Controlled Study

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Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis

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Referências científicas dos ativos

Coenzima Q10 (CoQ10)

  • Prahl, S., et al. "Effects of oral supplementation with coenzyme Q10 on skin aging and antioxidant status." Biofactors 39.2 (2013): 243-253. Acessar artigo
  • Free radicals and aging of the skin Acessar artigo

Ácido Hialurônico

  • Oe, M., et al. "Oral hyaluronan intake improves dry skin condition and reduces wrinkles: a randomized, placebo-controlled study." Clinical, Cosmetic and Investigational Dermatology 10 (2017): 267-273. Acessar artigo
  • Kawada, C., et al. "Ingested hyaluronan moisturizes dry skin." Nutrition Journal 13.1 (2014): 70. Acessar artigo
  • Sato, T., et al. "Clinical effects of oral administration of high-molecular-weight hyaluronic acid on facial skin aging." International Journal of Dermatology 53.10 (2014): 1185-1189. Acessar artigo
  • Maruyama, K., et al. "Effects of oral hyaluronan intake on skin conditions in healthy individuals." The Journal of Dermatology 46.8 (2019): 655-660. Acessar artigo

Trans-Resveratrol

  • Farris, P. K., et al. "Efficacy and tolerance of a nutrient supplement containing resveratrol, biotin, and coenzyme Q10 for improving skin condition: a randomized, placebo-controlled study." Journal of Clinical and Aesthetic Dermatology 7.9 (2014): 25-31. Acessar artigo
  • de Sá Coutinho, D., et al. "Resveratrol effects on skin: A comprehensive review of clinical trials." Nutrients 16.2 (2024): 239. Acessar artigo
  • Bautista, J. H., et al. "Resveratrol as a potential skin anti-aging agent: a review." Journal of Cosmetic Dermatology 18.6 (2019): 1646-1653 Acessar artigo
  • Varoni, E. M., et al. "Effects of resveratrol on human skin: A review of clinical evidence." Journal of Functional Foods 117 (2024): 106231. Acessar artigo
  • Huang, S., et al. "Beneficial effects of resveratrol on skin: a comprehensive review." Journal of Cosmetic Dermatology 22.4 (2023): 1097-1107. Acessar artigo

Ácido Ortosilícico Estabilizado em Maltodextrina (ch-OSA)

  • Barel, A., et al. "Effect of oral intake of choline-stabilized orthosilicic acid on hair tensile strength and morphology in women with fine hair." Archives of Dermatological Research 299.10 (2007): 499-505. Acessar artigo
  • Wickett, R. R., et al. "Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women." Journal of Cosmetic Dermatology 6.2 (2007): 96-101. Acessar artigo
  • Lassus, A. "The efficacy of silicon supplementation on nail strength." Journal of Trace Elements in Medicine and Biology 7.2 (1993): 115-117. Acessar artigo
  • Araújo, L. A., et al. "The use of silicon for skin and hair health: an update." Journal of Clinical and Aesthetic Dermatology 11.8 (2018): 31-36. Acessar artigo
  • Exley, C. "Silicon in diet and nutrition: is it necessary for human health?." Journal of Nutrition Health and Aging 25.1 (2021): 3-8. Acessar artigo

Vitamina A

  • Draelos, Z. D. "Cosmeceuticals: vitamins." Clinics in Dermatology 26.6 (2008): 614-617. Acessar artigo
  • Vollmer, D. L., et al. "The effects of nutritional factors on skin aging." Clinics in Dermatology 27.6 (2009): 643-647. Acessar artigo
  • Vierkötter, A., et al. "Dietary intake of carotenoids and vitamins A, C, and E in relation to risk of actinic keratoses." American Journal of Clinical Nutrition 93.4 (2011): 743-750. Acessar artigo

Hibisco em Pó

  • Riaz, M., et al. "Hibiscus sabdariffa L. – A phytochemical and pharmacological review." Fitoterapia 80.7 (2009): 369-375.

Amora Solúvel

  • Mastaloudis, A., et al. "Blackberry consumption improves cutaneous microcirculation and reduces oxidative stress in humans." Journal of Functional Foods 21 (2016): 422-430.

Zinco

  • Gupta, M., et al. "Zinc therapy in dermatology: a review." Dermatology Research and Practice 2014 (2014): 709152. Acessar artigo
  • Ogawa, Y., et al. "Zinc and skin disorders." Archives of Dermatology 109.4 (1974): 555-558. Acessar artigo
  • Choi, S., et al. "The role of zinc in wound healing." Biological Trace Element Research 144.1-3 (2011): 303-311 Acessar artigo
  • Lin PH, Sermersheim M, Li H, Lee PHU, Steinberg SM, Ma J. Zinc in Wound Healing Modulation. Nutrients. 2017 Dec 24;10(1):16. Acessar artigo

Cobre

  • Synergistic effect of copper and amino acid mixtures on the production of extracellular matrix proteins in skin fibroblasts Acessar artigo
  • Schagen, S. K., et al. "Discovering the link between nutrition and skin aging." Dermato-Endocrinology 4.3 (2012): 298-307 Acessar artigo

Selênio

  • Rayman, M. P. "Selenium and human health." The Lancet 356.9225 (2000): 233-241. Acessar artigo
  • Cai Z, Zhang J, Li H. Selenium, aging and aging-related diseases. Aging Clin Exp Res. 2019 Aug;31(8):1035-1047. Acessar artigo
  • https://pubmed.ncbi.nlm.nih.gov/10936378/ Acessar artigo
  • Schomburg, L. "Selenium, selenoproteins and human health: a review." Nutrients 9.1 (2017): 22 Acessar artigo

Biotina

  • A Review of the Use of Biotin for Hair Loss
  • Hochman, L. G., et al. "Brittle nails: response to daily biotin supplementation." Cutis 51.4 (1993): 303-305.

Vitamina B3 (Niacina)

Vitamina B5 (Ácido Pantotênico)

  • Vitamin B5 (Pantothenic Acid)

Vitamina C

  • Pullar, J. M., et al. "The roles of vitamin C in skin health." Nutrients 9.8 (2017): 866. Acessar artigo
  • DePhillipo, N. N., et al. "Efficacy of vitamin C supplementation on collagen synthesis and oxidative stress after musculoskeletal injuries: a systematic review." The American Journal of Clinical Nutrition 108.4 (2018): 703-716. Acessar artigo

Vitamina E

  • Rizvi, S., et al. "The role of vitamin E in human health and some diseases." Sultan Qaboos University Medical Journal 14.2 (2014): e157-e165.
  • Schagen, S. K., et al. "Discovering the link between nutrition and skin aging." Dermato-Endocrinology 4.3 (2012): 298-307. Acessar artigo
  • Jens J. Thiele, Swarna Ekanayake-Mudiyanselage, Vitamin E in human skin: Organ-specific physiology and considerations for its use in dermatology, Molecular Aspects of Medicine, Volume 28, Issues 5–6, 2007, Pages 646-667 Acessar artigo
  • Schagen SK, Zampeli VA, Makrantonaki E, Zouboulis CC. Discovering the link between nutrition and skin aging. Dermatoendocrinol. 2012 Jul 1;4(3):298-307. Acessar artigo

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